Deep learning has been evolving recently which allowed it to handle complex problems like big data, computer vision, and humanlevel control. One of the deep learning-powered applications recently emerged is called ”deepfake”. Deepfake algorithms have recently been a controversial development in Artificial Intelligence, because they use deep learning to generate fake yet realistic content based on an input dataset. As a result, many are concerned with the potential risks in terms of cyber-security as it causes threats to privacy, democracy, and national security. Multiple techniques were proposed to detect deepfake videos, however most cannot cope with the variety of the deepfake generation techniques. Therefore, in this study, we optimize one of the best existing deepfake detection methods based on Xception model. In particular, our proposed optimization scheme consists of a pre-processing phase performing advanced image enhancement on the videos in hand for highlighting the face features for better feature extraction as well fake content detection, which is preceded by a close-up dataset cleansing. Our experiments show that the proposed pre-processing optimization scheme had a major improvement to the performance of the Xception Binary Classifier- Inference model.